The 2025-26 college football season is inching closer, as we’re now under two months away from actual games being played. Between the transfer portal and NFL Draft, there are plenty of new names in the sport and familiar faces with new teams, so be sure to do your research before placing any wagers.
Most know Texas Longhorns QB Arch Manning (+600 favorite to win the Heisman trophy at BetMGM) and his famous family roots, but did you know Penn State (+800) has its best preseason national title odds since at least 2001, per Sports Odds History?
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One bettor in Arizona wagered $615,000 across three college football preseason futures bets and included Texas and Penn State in his wagers.
Throughout the season, we’ll keep track of the biggest reported futures wagers bettors are sweating as the College Football Playoff approaches.
Here is a running list of the largest wagers to win the CFP at legal U.S. sportsbooks, sorted by total liability:
T-1. $300,000 on Texas Longhorns to win national championship at +500 odds (BetMGM)
Bet wins $1.5 million
T-1. $200,000 on Penn State Nittany Lions to win national championship at +750 odds (BetMGM)
Bet wins $1.5 million
3. $115,000 on Clemson Tigers to win national championship at 13-1 odds (BetMGM)
Bet wins $1.495 million
