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Dolphins vs. Colts prediction: NFL Week 10 picks, odds

dolphins-vs.-colts-prediction:-nfl-week-10-picks,-odds
Dolphins vs. Colts prediction: NFL Week 10 picks, odds

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Indianapolis Colts quarterback Daniel Jones prepares to throw a pass against the Jacksonville Jaguars.
Indianapolis Colts quarterback Daniel Jones passes against the Jacksonville Jaguars in the first half of an NFL football game, Sunday, Nov. 1, 2026, in Jacksonville, Fla. AP Photo/Phelan M. Ebenhack

Two of the NFL’s worst teams will face off in Indianapolis on Sunday in a game oddsmakers are expecting to be a major offensive struggle. 

And I’m not expecting either offense to do much to prove them wrong.

After a trade deadline sell-off, Daniel Jones and Jonathan Taylor will lead a Colts offense with few weapons on the outside and depleted protection. 

Having already dealt away star guard Quenton Nelson, Indianapolis also shipped out wide receivers Josh Downs and Keenan Allen just before Tuesday’s deadline, leaving journeyman Laquon Treadwell and largely unproven options Ashton Dulin, Anthony Gould and Deion Burks to carry the load on the outside.

Things aren’t much prettier on the Miami side. 

The Dolphins will turn to Kyle McCord at quarterback for his first career start after Malik Willis was placed on injured reserve with a groin injury. 

Even with a healthy Willis, Miami has been one of the worst scoring teams in football, putting up 20 or more points in just two games this season. 

Ollie Gordon II of the Miami Dolphins runs the ball against the Detroit Lions.
Ollie Gordon II of the Miami Dolphins runs the ball against the Detroit Lions in Miami Gardens, Fla., Sunday, Nov. 8, 2026. Getty Images

The Dolphins’ defense has shown signs of life of late as well, holding the high-powered Lions to just 19 points last week and limiting Drake Maye’s Patriots to just 182 total passing yards a week earlier. 

The same can’t be said for the Colts, who surrendered 42 points to the Jaguars in Week 8 before allowing 27 against the Cowboys, but this Sunday is a much easier task.


Betting on the NFL?


While this number is already one of the lowest of Week 10, it still should be tough for these teams to get there. 

The play: Colts-Dolphins Under 40.5 points (-120, FanDuel Sportsbook)


Why Trust New York Post Betting

Dylan Svoboda is a versatile writer and analyst across many sports. He’s particularly knowledgeable about the big three — MLB, the NFL and the NBA.

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